GRK  2062 "Molecular Principles of Synthetic Biology"
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Open positions

Group Prof. Dr. Kai Papenfort

Project: Systems Biology of Bacterial Small RNAs

Papenfort group group focuses on the role of bacterial small RNAs in the stress response and virulence of major human pathogens, such as Vibrio cholerae. The project aims at a global understanding of sRNA-target mRNAs pairs in prokaryotic model organisms and involves state-of-the-art (e.g. next-generation-sequencing) technologies to identify RNA-duplexes at the genome-wide level. The molecular mechanisms underlying target recognition, base-pairing, and regulation will be further studied using molecular biology, genetics and biochemical approaches. We will use this information to build synthetic RNA regulators for tailored gene expression control in bacteria.

Applicants should have a strong background either in microbiology, bioinformatics, infection biology, molecular biology or biochemistry.

Place of work: Ludwig-Maxilimilians-Universität München, LMU Biocenter, Großhaderner Str. 2-4, D-82152 Martinsried

Group Prof. Dr. Dario Leister

Project: Towards improving photosynthesis at the interface of molecular and synthetic biology

The project is at the interface of plant molecular biology, adaptive evolution and synthetic biology. We are working with the model cyanobacterium Synechocystis and the model plant Arabidopsis and aim to identify factors involved in stress tolerance in the prokaryote than will be then transferred en bloc into the model plant, bypassing generations of conventional breeding.

The candidate should have a solid background in biochemistry and molecular biology and preferably also in plant sciences. We are searching for a highly motivated PhD student who is willing to work in a competitive research field.

Place of work: Ludwig-Maxilimilians-Universität München, LMU Biocenter, Großhaderner Str. 2-4, D-82152 Martinsried


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